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Sildenafil is a powerful and selective inhibitor of cGMP-unique phosphodiesterase style 5 (PDE5), that's to blame for degradation of cGMP while in the corpus cavernosum. The molecular composition of sildenafil is similar to that of cGMP and acts being a competitive binding agent of PDE5 while in the corpus cavernosum, leading to a lot more cGMP and